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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COPS6
All Species:
25.76
Human Site:
Y241
Identified Species:
56.67
UniProt:
Q7L5N1
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7L5N1
NP_006824.2
327
36163
Y241
R
V
K
L
I
L
E
Y
V
K
A
S
E
A
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001100125
326
36044
Y240
R
V
K
L
I
L
E
Y
V
K
A
S
E
A
G
Dog
Lupus familis
XP_536866
321
35704
Y235
R
V
K
L
I
L
E
Y
V
K
A
S
E
A
G
Cat
Felis silvestris
Mouse
Mus musculus
O88545
324
35862
Y238
R
V
K
L
I
L
E
Y
V
K
A
S
E
A
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NUC2
318
35518
Y232
R
V
R
L
I
L
E
Y
V
R
A
A
E
G
G
Zebra Danio
Brachydanio rerio
NP_001017768
297
33615
E219
V
K
A
V
Q
A
G
E
V
P
F
N
H
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCY3
341
38287
Y255
R
I
K
I
V
L
Q
Y
I
R
D
V
E
A
G
Honey Bee
Apis mellifera
XP_393678
338
37998
Y252
R
V
K
L
V
L
K
Y
V
Q
A
V
Q
N
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192086
297
33638
E219
V
K
A
V
Q
S
G
E
V
P
M
N
H
E
I
Poplar Tree
Populus trichocarpa
XP_002330530
306
34249
M225
L
H
H
Y
L
V
A
M
Q
K
G
E
I
P
C
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8W206
317
35640
Q231
S
R
I
R
V
L
Y
Q
N
L
A
A
M
Q
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99
97.5
N.A.
97.8
N.A.
N.A.
N.A.
N.A.
88.6
83.7
N.A.
56.8
62.7
N.A.
70
Protein Similarity:
100
N.A.
99
97.8
N.A.
98.4
N.A.
N.A.
N.A.
N.A.
93.8
87.7
N.A.
75
76.3
N.A.
80.7
P-Site Identity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
73.3
6.6
N.A.
46.6
60
N.A.
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
N.A.
N.A.
N.A.
N.A.
93.3
20
N.A.
86.6
86.6
N.A.
20
Percent
Protein Identity:
35.4
N.A.
N.A.
34.5
N.A.
N.A.
Protein Similarity:
56.8
N.A.
N.A.
56.5
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
0
0
10
10
0
0
0
64
19
0
46
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
46
19
0
0
0
10
55
19
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
19
0
0
0
10
0
0
10
64
% G
% His:
0
10
10
0
0
0
0
0
0
0
0
0
19
0
0
% H
% Ile:
0
10
10
10
46
0
0
0
10
0
0
0
10
0
19
% I
% Lys:
0
19
55
0
0
0
10
0
0
46
0
0
0
0
10
% K
% Leu:
10
0
0
55
10
73
0
0
0
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
10
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
19
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
19
0
0
0
10
0
% P
% Gln:
0
0
0
0
19
0
10
10
10
10
0
0
10
10
0
% Q
% Arg:
64
10
10
10
0
0
0
0
0
19
0
0
0
0
0
% R
% Ser:
10
0
0
0
0
10
0
0
0
0
0
37
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
19
55
0
19
28
10
0
0
73
0
0
19
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
10
64
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _